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Histological Classification of Hematopoietic Tumors of Domestic Animals

TUMORS OF LYMPHOID SYSTEM

1. B-Cell Lymphoid Neoplasms
1.1 Precursor B-cell neoplasms
1.1.1 B-cell lymphoblastic leukemia/lymphoma
1.2 Mature B-cell neoplasms
1.2.1 B-cell chronic lymphocytic leukemia/lymphoma
1.2.2 B-cell lymphocytic lymphoma intermediate type (LLI)
1.2.3 Lymphoplasmacytic lymphoma (LPL)
1.2.4 Follicular lymphomas
1.2.4.1 Mantle cell lymphoma (MCL)
1.2.4.2 Follicular center cell lymphoma I
1.2.4.3 Follicular center cell lymphoma II
1.2.4.4 Follicular center cell lymphoma III
1.2.4.5 Nodal marginal zone lymphoma
1.2.4.6 Splenic marginal zone lymphoma
1.2.5 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
1.2.6 Hairy cell leukemia
1.2.7 Plasmacytic tumors
1.2.7.1 Indolent plasmacytoma
1.2.7.2 Anaplastic plasmacytoma
1.2.7.3 Plasma cell myeloma
1.2.8 Large B-cell lymphomas
1.2.8.1 T-cell-rich B-cell lymphoma
1.2.8.2 Large cell immunoblastic lymphoma
1.2.8.3 Diffuse large B-cell (noncleaved, cleaved) lymphoma
1.2.8.4 Thymic B-cell lymphoma (mediastinal B)
1.2.8.5. Intravascular large B-cell lymphoma
1.2.9 Burkitt-type lymphoma
1.2.9.1 High-grade B-cell lymphoma, Burkitt-like

2 T-Cell and NK-Cell Lymphoid Neoplasms
2.1 Precursor T-cell neoplasms
2.1.1 T-cell lymphoblastic leukemia/lymphoma
2.2 Mature T-cell and NK neoplasms
2.2.1 Large granular lymphoproliferative disorders (LGL)
2.2.1.1 T-cell chronic lymphocytic leukemia
2.2.1.2 T-cell LGL lymphoma/leukemia
2.2.1.3 NK-cell chronic lymphocytic leukemia
2.2.2 Cutaneous T-cell neoplasms
2.2.2.1 Cutaneous epitheliotropic lymphoma (CEL)
2.2.2.1.1 CEL, mycosis fungoides type
2.2.2.1.2 CEL, pagetoid reticulosis (Woringer-Kolopp) type
2.2.2.2 Cutaneous nonepitheliotropic lymphoma
2.2.3 Extranodal/peripheral T-cell lymphoma (PTCL)
2.2.3.1 PTCL, mixed lymphoid type
2.2.3.2 PTCL, mixed inflammatory type
2.2.4 Adult T-cell like lymphoma/leukemia
2.2.5 Angioimmunoblastic lymphoma (AILD)
2.2.6 Angiotropic lymphoma
2.2.6.1 Angiocentric lymphoma
2.2.6.2 Angioinvasive lymphoma
2.2.7 Intestinal T-cell lymphoma
2.2.8 Anaplastic large cell lymphoma (ALCL)

3 Miscellaneous Tumors
3.1 Mast cell tumor
3.2 Hodgkin-like lymphoma
3.3 Thymoma
3.4 Thymic carcinoma (malignant thymoma)
3.5 Myelolipoma
3.6 Malignant fibrous histiocytoma

4 Benign Lymphoid Proliferations
4.1 Follicular lymphoid hyperplasia
4.2 Atypical follicular lymphoid hyperplasia
4.3 Paracortical lymphoid hyperplasia


TUMORS OF THE MYELOID SYSTEM

1 Malignant Myeloid Proliferations
1.1 Precursor myeloid leukemia
1.1.1 Acute myeloid leukemia/undifferentiated leukemia (AML M0)
1.1.2 Acute myeloid leukemia without maturation (AML M1)
1.1.3 Acute myeloid leukemia with maturation (AML M2)
1.1.4 Acute promyelocytic leukemia (AML M3)
1.1.5 Acute myelomonocytic leukemia (AML M4)
1.1.6 Acute monoblastic leukemia (AML M5A)
1.1.7 Acute monocytic leukemia (AML M5B)
1.1.8 Erythroleukemia (AML M6A)
1.1.9 Erythremic myelosis (AML M6B)
1.1.10 Acute megakaryoblastic leukemia (AML M7)
1.2 Chronic myelogenous leukemias (CML)
1.2.1 CML, neutrophilic
1.2.2 CML, eosinophilic
1.2.3 CML, monocytic
1.2.4 Polycythemia vera
1.2.5 Megakaryocytic myelosis/essential thombocythemia
1.3 Myelodysplastic syndromes
1.3.1 Idiopathic myelofibrosis/myeloid metaplasia (MMM)
1.3.2 Chronic myelomonocytic leukemia (CMML)
1.3.4 Refractory anemia with excess blasts (RAEB)

2 Solid Myeloid Proliferations
2.1 Cutaneous histiocytoma
2.2 Cutaneous histiocytosis (cutaneous reactive histiocytosis)
2.3 Systemic histiocytosis (systemic reactive histiocytosis)
2.4 Histiocytic sarcoma/malignant histiocytosis
2.5 Granulocyitc sarcoma

3 Benign Myeloid Proliferations
3.1 Leukemoid reaction \
3.2 Leukopenia with left shift
3.3 Post-toxic response
3.4 Loeffler-like syndrome
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