Notes
Outline
What’s New and Important in Ferret Medicine
(or Fifty Things That Vets Need to Know)
Bruce H. Williams, DVM, DACVP
Chairman, AFIP Dept. of Telemedicine
(202) 782-2392
Email:  williamsb@afip.osd.mil
Mustela putorius furo
Therapeutic Considerations
Ferrets do much better at home.
Owners can administer fluid therapy very competently.
Nutritional supplementation is a must with sick ferrets.
Empiric use of antibiotics, while convenient, may run counter to patient’s long-term interests.
Antibiotic Considerations
Improper use may hamper diagnostic testing.
Antibiotics may mask clinical signs.
Antibiotics may result in their own clinical signs
Antibiotics should be employed for specific reasons (get the culture and sensitivity first!)
Surgical Considerations
(or How to Decrease Unexpected Mortality)
Use inhalation anesthesia without premeds.  Injectable anesthetics are very unpredictable in ferrets.
Isoflurane safest with mask or tank induction.
Heating pad suggested during and after surgery – ferrets get hypothermic very quickly.
Should provide fluid therapy for all surgeries more serious than neutering
Clin Path Considerations
(A Ferret is Not a Cat nor is it a  Dog)
Ferrets normally have high PCV and low WBC.
Persistent lymphocytosis does NOT mean lymphoma.
Hepatic enzymes are usually elevated simply as a result of inanition in the ferret.
Older ferrets are commonly mildly hypoproteinemic due to chronic bowel inflammation due to coronavirus or Helicobacter infection).
Ferrets with adrenal disease rarely have abnormalities on routine CBC/chemistry.
Ferret Coronavirus
Ferret Coronavirus
Ferret Coronavirus
Ferret Coronavirus
Ferret Coronavirus
Acute Lesions
Vacuolar degeneration and necrosis of villar tip enterocytes
Villar blunting
Ferret Coronavirus
Ferret Coronavirus
Ferret Coronavirus
Aleutian Disease
Aleutian Disease
Aleutian Disease
Aleutian Disease
Helicobacter mustelae
Ubiquitous disease - all ferrets infected by 2 wks of age.
Contributes to debility in older ferrets.
10% will show clinical signs during lifetime.
Gastric damage due to physical destruction of gastric mucosa coupled with profound lymphoplasmacytic inflammation
Associated with gastric ulcers
Gross lesions usually absent
Helicobacter mustelae
Helicobacter mustelae
Helicobacter mustelae
Adrenal-associated endocrinopathy
Adrenal-associated endocrinopathy
Adrenal-associated endocrinopathy
Adrenal-associated endocrinopathy
Islet cell tumor (Insulinoma)
Islet cell tumor
Islet cell tumor
Malignant lymphoma (Lymphosarcoma)
Malignant lymphoma (Lymphosarcoma)
Malignant lymphoma (Lymphosarcoma)
Slide 33
Malignant lymphoma (Lymphosarcoma)
Gastric Ulcers
Gastric Ulcers
Gastric Ulcers
Gastrointestinal foreign bodies
Gastrointestinal foreign bodies
Proliferative colitis
Proliferative colitis
Proliferative colitis
Proliferative colitis
Eosinophilic enteritis
Eosinophilic enteritis
Eosinophilic enteritis
Eosinophilic enteritis
Splenomegaly
Splenomegaly
Cardiomyopathy
Cardiomyopathy
Cardiomyopathy
Cardiomyopathy
Slide 54
Canine Distemper
Canine Distemper
Canine Distemper
Canine Distemper
Canine Distemper
Canine Distemper
Canine Distemper
Canine Distemper
Rabies
Rabies
Neural Tube Defects
Neural Tube Defects
Common Incidental Findings
Common Incidental Findings
Common Incidental Findings
Common Incidental Findings
Common Incidental Findings
Common Incidental Findings
Common Incidental Findings
Neoplasms
Neoplasms
Neoplasms
Neoplasms
Other Neoplastic Goodies
Other Neoplastic Goodies
Other Neoplastic Goodies
Other Neoplastic Goodies
Other Neoplastic Goodies
Other Neoplastic Goodies
Actinomyces sp.
(this slide dedicated to Harley)
Slide 85