SARS Case 1 Autopsy, Singapore
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| Radiograph from day 9 reveals patchy areas of consolidation primarily in the mid and lower lung zones bilaterally. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved.) |
Radiograph from day 11 demonstrates diffuse, symmetric involvement of both lungs. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved.) |
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| Radiograph from day 13 reveals worsening. The patient is now intubated. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved.) |
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| Figure 1. Homogeneous appearing hyaline membranes (arrow) line edematous alveolar walls (H&E stain, 200x). |
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| Figure 2. Organizing DAD is characterized by loose fibroblastic proliferation in alveolar spaces (arrow) and within the interstitium (arrowhead) and type II pneumocyte hyperplasia (H&E stain, 100x). |
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| Figure 3. Acute bronchopneumonia is characterized by polymorphonuclear leukocytes filling alveolar spaces, and in this case is associated with alveolar hemorrhage (H&E stain, 200x). |
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| Figure 4. Cytologically atypical epithelial cells are present within alveolar spaces (H&E, 400x). |
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| Figure 5. Digital slide of diffuse alveolar damage (H&E). |