SARS Case 2
Autopsy, Singapore
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(Click image for larger size.) |
| Radiograph from day 16 reveals patchy areas of ground glass opacity and consolidation bilaterally. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved) |
Radiograph from day 22 demonstrates progression with increasing bilateral consolidation. The patient is now intubated and there is evidence of hyperinflation. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved) |
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| Radiograph from day 25 demonstrates an air-containing cyst in the right mid lung field consistent with a pneumatocele. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved) |
Radiograph 12 hours later reveals rapid development of multiple pneumatoceles just prior to death. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved) |
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| Figure 1. Hyaline membranes line alveolar walls and a fibrin microthrombus is present within the lumen of a small vessel (arrow) (H&E stain, 200x). |
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| Figure 2. Cytologically atypical epithelial cells with cytomegaly, nucleomegaly, focal nuclear clearing, and multinucleation are present within alveolar spaces (H&E stain 800x). |
(Click image to view the digital slide.) |
| Figure 3. Digital slide of diffuse alveolar damage (H&E). |
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