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SARS Case 3
Autopsy, Singapore


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Radiograph on day 8 reveals consolidation in left mid and lower lung zones. There is minimal involvement in the right lower lung zone. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved) Radiograph on day 10 reveals rapid progression with bilateral areas of consolidation. The patient is now intubated. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved)

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Radiograph on day 18 demonstrates better inflation of both lungs most likely related to increased ventilator support. (copyright 2003, contributed by Tan Tock Seng Hospital, Singapore, all rights reserved)

 


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Figure 1. Hyaline membranes line alveolar walls (H&E stain, 200x).

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Figure 2. Hyaline membranes line infarcted alveolar walls (H&E stain, 200x).

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Figure 3. Multinucleated atypical epithelial cells and organizing exudate (arrow) are seen within alveolar spaces (H&E stain, 400x).

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Figure 4. Digital slide of diffuse alveolar damage (H&E).
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Website created: May 1, 2003. Last updated: February 18, 2004