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Monkeypox Case 3

A facility outbreak of a necrotizing and pustular rash affected a variety of species at a primate center, including both Old and New World Primates.

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Figure 1. Typical gross presentation of a monkeypox lesion (“pock) in a macaque. The reddened and depressed center is necrotic; circumferentially, the epithelium is hyperplastic.

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Figure 2. Monkeypox in an unidentified new world primate. The plantar lesions are traumatized, as opposed to those on the legs (above – or right, left or some other direction.)

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Figure 3. Monkeypox in an unidentified new world primate.

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Figure 4. Full-thickness necrosis (ulcer) of the tongue in a cynomolgus monkey infected with monkey pox. (HE, 2x)

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Figure 5. Intracytoplasmic viral inclusions within degenerate epithelial cells at the edge of an ulcer. (HE, 50x)

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Website created: June 18, 2003. Last updated: July 1, 2003